In Vitro Fertilization (IVF) is the most common advanced and widely accepted assisted reproductive technology (ART) treatment that has helped thousands of couples grow their families since it was first successfully performed in 1978. The procedure involves removing eggs from a woman’s ovaries and fertilizing them in an embryology lab with fresh or frozen sperm (from a partner or donor). The resulting embryos are cultured and transferred back into the uterus to achieve pregnancy.
Once your diagnostic testing is complete, we will review your treatment options. Many patients are surprised to learn that IVF is not their only treatment option. However, IVF can be either the only or the most effective fertility treatment if you have :
- Tubal issues (blocked, damaged)
- Tubal removal or sterilization
- Male factor infertility (impacting sperm quality or quantity)
- Genetic disorders
- Unexplained infertility, Ovulation issues when IUI was not successful
- Fertility preservation
- LGBTQ+ family building
- Single parent
At Precision IVF, whenever feasible, we start with basic, "low-tech" treatments like IUI and then transition to IVF when cheaper and less invasive treatment options are not successful. Studies show that after three to four treatment cycles, success rates with IUI begin to decline sharply. By moving to IVF treatment we are increasing your chances of success. Our cutting-edge IVF treatment protocols and customized treatment plans are designed to give you the best chances of achieving your dream family. Dr. Arya, as well as every member of our experienced team at Precision IVF and associated lab, is personally invested in your success. We take pride in providing affordable care in a compassionate environment and we would be honored to be a part of your journey.
At Precision IVF we provide patients with a personalized treatment plan that is designed to meet your individual needs and family-building goals. Our standard IVF treatment process includes the following steps:
Patients receive birth control medication for a few weeks, generally less than a month to synchronize the growth of follicles.
Ovarian stimulation involves taking hormone medications for approximately 8-14 days to stimulate multiple follicle development to increase the number of eggs retrieved. Patients are closely monitored by ultrasound and blood workups. Once follicle sizes and hormones reach appropriate levels, a “trigger shot” (HCG or Lupron) is administered to initiate the final egg maturation.
The egg retrieval is scheduled approximately 35 hours after the trigger shot. This minor surgical procedure is performed under ultrasound guidance and has a guide to insert a thin needle through the wall of the vagina into the ovary to collect eggs from each follicle. This procedure may last 15 to 30 minutes and is usually done on an outpatient basis under sedation.
This is usually done on the day of the egg retrieval. Fresh or frozen sperm may be used and will be “washed” (or processed) using advanced laboratory techniques separating the sperm from the seminal fluid, increasing the number of motile sperm and improving the likelihood for fertilization. In instances when sperm collection on the day of egg retrieval looks stressful, semen sample can be collected ahead of time and cryopreserved in the andrology lab as a backup option. Some men with severe male factor infertility may require a testicular biopsy for extraction of sperm for IVF.
Eggs are then fertilized either conventionally (by placing the egg and sperm in a dish to allow fertilization) or by injecting a single sperm directly into the egg (intracytoplasmic sperm injection or ICSI). ICSI is a micromanipulation procedure that allows fertilization even with very low sperm count.
A fertilization check is done approximately 18-19 hours after conventional insemination or ICSI. Fertilization is the union of male and female reproductive cells (sperm and egg) to produce a fertilized egg (zygote).
The embryo(s) are then cultured to grow in the laboratory for 5-7 days. On the day of embryo transfer (done either on day 3 or day 5 for fresh embryo transfer) the embryo or blastocyst with the highest morphological grade is selected for transfer. Preimplantation genetic testing (PGT) is performed at this time for patients who choose this testing. Remaining embryos can be cryopreserved for future transfer attempts.
Embryo transfer requires the use of a small catheter to draw up the selected embryo(s) and to transfer them into the woman’s uterine cavity. This procedure is generally painless and usually does not require anesthesia. For best results we use ultrasound guidance for accurate catheter localization and transfer of the embryo into the uterine cavity. We follow the American Society for Reproductive Medicine (ASRM) guidelines and typically transfer one or two embryos at a time, reducing the likelihood of multiple births. Upon completion of the transfer, the embryo(s) should “hatch” from their outer shell and implant into the uterine wall.
A blood test is performed typically nine to 11 days after transfer to determine if a woman is pregnant. If embryo implantation has occurred, the HCG hormone will be detected in the bloodstream and the woman will be considered pregnant. Patients who achieve pregnancy will schedule a follow-up visit for blood work and an ultrasound. For those patients who were not able to achieve pregnancy, we will schedule a consultation to review your cycle in detail and discuss further options to continue or alter the treatment.
Depending on your diagnosis and treatment plan, you may choose to include add-on services as a part of your IVF cycle. These can include:
Micro/Mini IVF is a very unique and simplified approach, reducing the cost, number of injections, and risk of hyperstimulation while maintaining good success rates. There are some studies that suggest Mini-IVF may be a better solution for low ovarian reserve and/or older patients.
Dr. Arya will work with you to determine if these options are right for you based on your needs and personal preferences.
At Precision IVF we offer comprehensive care for couples and individuals with infertility, ranging from simple medical therapy to surgery to advanced assisted reproductive technologies.
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